Marie Veronique: The Senolytic Series

An intentional approach to skin aging, barrier health, and the science of longevity.

A New Chapter in Skin Longevity

At Cleo, we believe skincare is about understanding the skin, supporting its natural functions, and choosing ingredients with intention. As our understanding of skin health continues to evolve, one area of growing interest is skin longevity: an approach that looks beyond temporary results to explore the biological processes that influence how our skin changes over time.

Marie Veronique's Senolytic Series reflects this shift, bringing emerging longevity research into a two part topical skincare approach featuring the Senolytic Serum and Senolytic Balm. Designed to complement one another, these formulas explore cellular health, antioxidant support, collagen maintenance, and barrier nourishment.

We are excited to now carry the Senolytic Balm in our retail collection at Cleo, and to share more of the science behind this innovative series.

Understanding the Science of Skin Longevity

As skin ages, changes in cellular function, collagen production, oxidative stress, and barrier integrity can influence its resilience and appearance. One process researchers are investigating is cellular senescence.

Senescent cells are cells that have stopped dividing but remain active. They can release signaling molecules that influence surrounding cells and contribute to changes in the tissue environment. Because the accumulation of these cells is associated with aging, researchers are exploring compounds known as senolytics, which are studied for their potential to selectively target senescent cells.

One ingredient at the center of Marie Veronique's approach is fisetin, a naturally occuring flavonoid found in certain fruits and vegetables. Fisetin has attracted attention in longevity research for its potential senolytic activity. While this research remains ongoing, it offers an exciting perspective on the future of skincare: supporting the conditions associated with healthier skin function rather than focusing exclusively on the visible signs of aging.

Meet the Senolytic Series

Marie Veronique developed two complementary formulas that approach skin longevity from different angles. Each features fisetin, delivered in a different formulation, alongside ingredients selected for additional skin supportive benefits.

Senolytic Serum -

The lightweight Senolytic Serum is designed to provide targeted skin longevity support. Its formula features encapsulated fisetin, which is designed to help protect this sensitive ingredient from degradation in the water based formula. The serum also contains astragalus root and magnesium ascorbyl phosphate, a stable vitamin C derivative. Together, these ingredients provide antioxidant support and are intended to support collagen related processes and skin resilience. The serum layers easily into an evening skincare ritual and is formulated for those looking to explore longevity focused skincare across a range of skin types.

Senolytic Balm-

The Senolytic Balm builds on the series longevity focused approach with a rich lipid based formula designed to nourish the skin and support barrier integrity. Its formula features fisetin alongside resveratrol, CoQ10, and tetrahexyldecyl ascorbate, an oil soluble form of vitamin C. These ingredients offer antioxidant support and complement the balms replenshing blend of jojoba seed oil, shea butter, camellia seed oil, and squalane. The balm is a comforting buttery treatment that helps seal in moisture, reduce water loss, and leave the skin feeling supple, replenished and luminous. This balm is especially suited to skin that feels dry, depleted, or in need of nourishment.

An Intentional Approach to Aging

Aging is a natural part of being human, reflected in the subtle and beautiful ways our skin changes over time. Rather than viewing these changes as something to resist, we can begin to approach them with greater understanding, curiosity, and care.

As our understanding of skin health evolves, so does the conversation around aging. The emerging field of skin longevity invites us to look beyond the surface and consider the biological processes that influence our skins resilience, function, and vitality over time.

Embracing Every Season of Skin

An intentional approach to aging begins with a shift in perspective. We can honor the skin we have today while caring for the skin we will have tomorrow.

This means choosing consistency over urgency, nourishment over excess, and education over unrealistic expectations. It means recognizing that skincare is one part of a larger picture that includes rest, nourishment, sun protection, and the everyday practices that support our overall well-being.

At Cleo, our goal is to help you make informed choices that feel aligned with your skin, your values, and the way you want to care for yourself.

Discover Marie Veronique’s Senolytic Balm at Cleo, and explore a more thoughtful approach to skin longevity.

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We cannot stop time, but we can choose to meet each stage of life with intention, nourishment, and care.

We can’t wait to support you,

Cleo Team